DISCORDANT GENE EXPRESSION SIGNATURES AND RELATED PHENOTYPIC DIFFERENCES IN LAMIN A- AND A/C-RELATED HUTCHINSON-GILFORD PROGERIA SYNDROME (HGPS).

Discordant gene expression signatures and related phenotypic differences in lamin A- and A/C-related Hutchinson-Gilford progeria syndrome (HGPS).

Hutchinson-Gilford progeria syndrome (HGPS) is a genetic disorder displaying features reminiscent of premature senescence caused by skateboards germline mutations in the LMNA gene encoding lamin A and C, essential components of the nuclear lamina.By studying a family with homozygous LMNA mutation (K542N), we showed that HGPS can also be caused by m

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Laser Interstitial Thermotherapy (LITT) in Recurrent Glioblastoma: What Window of Opportunity for This Treatment?

Laser Interstitial Thermotherapy is a minimally invasive treatment option in neurosurgery for intracranial tumors, including recurrent gliomas.The technique employs the thermal ablation of target tissue to achieve tumor control with real-time monitoring Nails of the extent by magnetic resonance thermometry, allowing targeted thermal injury to the l

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Lightning Detection and Imaging Based on VHF Radar Interferometry

In this study, detection and three-dimensional (3D) imaging of lightning plasma channels are presented using radar interferometry.Experiments were carried out in Leshan, China with a 48.2 MHz VHF radar configured with an interferometric antenna array.The typical characteristics of lightning echoes are studied in the form of amplitude, phase, and do

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Connecting RDM Services

The Research Data Management Organiser (RDMO) supports researchers in the creation of data management plans (DMPs).The open source software has established itself widely across Germany as the standard DMP tool.For its broader adoption, integration with home other services for research data management is key.In this paper we reflect on the potential

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Numerical Weather Prediction Correction Strategy for Short-Term Wind Power Forecasting Based on Bidirectional Gated Recurrent Unit and XGBoost

Accurate short-term wind power forecasting (WPF) plays a crucial role in grid scheduling and wind power accommodation.Numerical weather prediction (NWP) wind speed is the fundamental data for short-term WPF.At present, reducing NWP wind speed forecast errors contributes to improving the accuracy of WPF from the perspective of data quality.In this a

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